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More information References Worldwide smoking statistics [online]

Policy responses in recent years have included banning common carrier delivery of cigarettes,[6] greater law enforcement activity on interstate roads,[7] differential tax rates near low-tax jurisdictions,[8] and cracking down on tribal reservations that sell tax-free cigarettes.[9] However, the underlying problem remains: high cigarette taxes amount to a price prohibition on the legal product in many U.S

But, as you say, it may help to shield the innocent from the brute arm of the law

Genomic imprinting: employing and avoiding epigenetic processes