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C Ray Greek of Americans for Medical Advancement states that Animal experiments failed notoriously to demonstrate a smoking-cancer connection for over half a centuryIf the greatest killer of our time was promoted by physicians based on animal experiments, there is obviously something terminally wrong with the system. 10 A 2015 paper drawing on more than 50 recent toxicology studies, demonstrated the superiority of widely available modern, non-animal models over inaccurate animal tests for measuring the toxicity of tobacco products

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Alshbool and Rivera contributed to conceptualization of studies, analyzed data, and wrote manuscript