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Regular smoking and even secondhand smoking have been tied to a number of cardiovascular and respiratory illnesses, including coronary artery disease and chronic obstructive pulmonary disease

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If you use [migraine] rescue medication too frequently, it can lead to rebound, says Roderick Spears, MD, a neurologist and associate professor of migraine research and clinical sciences at Brown University in Providence, Rhode Island

Combined with a 50mg nicotine strength, it has quite a bit of kick