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In some cases, e-cigarettes stimulate the production of ROS in alveolar macrophages, causing lung epithelial damage and neutrophil influx at injury sites, resulting in aggravated inflammation, mucus production, and destruction of alveolar cells, leading to airway obstruction [53]

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This mechanism also makes smoking the most relevant biological mediator of co-morbid cardiovascular disease in people with BD (38)

As an abused drug, GHB is usually consumed as a clear oral solution and is mostly used by men aged 20-30, primarily in West Sweden around Gothenburg