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Common signs include the inability to quit despite attempts, strong cravings for tobacco, continued use despite health problems, and prioritizing tobacco use over other activities or responsibilities

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For the sake of childrens health, Gottlieb encourages FDA to remove some or all of these ENDS products from the market pending approval of premarket review applications. He suggests that the public health consequences of the youth vaping epidemic may be so severe that FDA can decline to authorize the products for sale
