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The addictive properties of tobacco primarily stem from nicotine, which rapidly reaches the brain upon inhalation or absorption through the mucous membranes, according to an article by the Food and Drug Administration 2024, titled Nicotine Is Why Tobacco Products Are Addictive Once in the brain, nicotine binds to nicotinic acetylcholine receptors, stimulating the release of neurotransmitters, including dopamine, which creates pleasurable sensations and reinforces the behavior of tobacco use

(Part 9, Section 9.7) 12A.2.4.7 Health warnings for bidis and smokeless tobacco Parts 7 and 8 of the Standard set out the content of health warnings for bidis and smokeless tobacco respectively, both of which were required to have warning statements only

It usually takes a moment for full adhesion