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NRT is not contraindicated in smokers with cardiovascular or pulmonary disease.48-53 Some trials have demonstrated that smokers with a history of chronic alcoholism are less likely to quit than smokers who do not suffer from this condition.54,55 However, a recent study showed that the probability of quitting with bupropion is identical in all patients, irrespective of whether or not they have a history of alcoholism.56 Psychiatric History

However, there is no international consensus on how to manage pregnancies complicated by smoking other than to offer smoking cessation support

Each subcode may be further combined with aortic regurgitation or insufficiency specificity