does john goodman smoke cigarettes smoking a cigarette outside Regent Hotel Berlin, Germany - 08.02.09 Stock Photo Judge denies John Goodman's bid
Description
Dosage Adjustment for Known CYP2D6 poor metabolizers and patient taking concomitant CYP2D6 inhibitors, CYP3A4 inhibitors, and/or CYP3A4 inducers CYP2D6 Poor Metabolizers: Should not be used (Health Canada)

Two Oscar nominations, one on either side of Gigi (her biggest hit): Llli and The L Shaped Room
The total ban on tobacco, including waterpipe and e-cigarette use should include health facilities, governmental and public buildings, restaurants and cafes, schools and educational facilities, universities, sports facilities, transportation, and private and public workplaces

This implies you will need to smoke more to achieve the same effect
