are tobacco leaves poisonous Green Sickness https://www.cdc.gov/tobacco/nicotine-pouches

The curing process follows a clear sequence: Yellowing stage: Temperature is held low (around 3540C) to allow the leafs chlorophyll to break down

1982, Littleton, Massachusetts: John Wright Blane D, Hart CL, Smith GD, Gillis CR, Hole DJ, Hawthorne VM: Association of cardiovascular-disease risk-factors with socioeconomic position during childhood and during adulthood

However, the suitability of their inclusion in the model should be individually assessed for each country 28

Am J Respir Cell Mol Biol 19(5):819825 Taner CB et al (2001) Treatment with endothelin-receptor antagonists increases NOS activity in hypercholesterolemia