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The porous nature of the mineral allows the pipe to season and will change color over time and use
An interaction between smoking (as ever/never) and TNFRSF1B risk genotypes GG or GT was found, with an OR of 5.42 (95%CI 2.48, 11.84) for SLE in the presence of both factors and a significant attributable proportion of 0.49 (49% of the excess risk of SLE among smokers with a G allele was due to an interaction)
