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Moreover, epigenetic influences play a significant role in radon carcinogenesis, including DNA methylation, alteration of histones, and microRNA dysregulation [192]

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Indeed, a recent analysis projected that even if all risk reduction targets are met under the United Nations Agenda for Sustainable Development, which sets a target to reduce premature mortality from non-communicable diseases by one-third by 2030, this goal could be met for cardiovascular disease and chronic respiratory diseases, but not for cancer (75)

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