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The AMAs foundation is committed to its own study devoted primarily to determine which significant human ailments may be caused or aggravated by smoking, how they may be caused, the particular element or elements in smoke that may be the causal or aggravating agent, and methods for the elimination of such agent. The announcement of the project indicated that it would be financed by a substantial contribution from the American Medical Association and that contributions would be solicited from other sources, with the understanding that contributions would be accepted only if given without restrictions

Among current adult e-cigarette users, the proportion of never smoked cigarettes was highest among 18-24 year olds (56.0%) and lower among older age groups

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Summary Keywords adolescents, e-cigarettes, nicotine addiction, prevention strategies, public health, vaping Citation Fainardi V, Barbetta E, Petz M, Rizzo L, Ruberti F and Esposito S (2026) The new nicotine epidemic: understanding the systemic harms of e-cigarettes in the adolescent population