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It consists of two items, including the time to the first cigarette after waking and the number of cigarettes smoked in a day 13,14

doi: 10.1016/j.pharmthera.2018.11.010 52 Kabat-ZinnJ

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The FAK protein participates in cell adhesion, invasion, migration, proliferation and apoptosis and is involved in tumor occurrence, development and prognosis (Daneial et al., 2017)
