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Differential assessment Cannabis dependence must be differentiated from: Cannabis abuse / harmful use without dependence features Cannabis-induced psychiatric conditions (e.g., psychosis, mood disorders) Other substance use disorders or comorbid conditions Accurate diagnosis requires thorough history-taking, standardized screening tools (e.g., CUDIT-R), collateral reports when available, and clear documentation of symptom onset, course, and functional impact

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His Introduction to Loci was published posthumously in 1679