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Ultimately, since irinotecan-TACE is a locoregional therapy that can be repeated for progressive or new lesions or followed up by other locoregional or systemic therapies, early response and disease control should not be neglected. Moreover, the authors emphasise the potential for irinotecan-TACE to be combined with other treatment strategies to either intensify the liver-directed treatment or target extrahepatic disease

Incidence rates for tobacco-related cancers are still higher among men (250 per 100,000 persons) than women (148 per 100,000 persons)

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for centuries, it has been used as an insecticide