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Stimulation of -cell proliferation secondary to stimulating GLP-1R is usually only observed in young animals (during periods characterized by preserved proliferative capacity), and not in older rodents [548]

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doi: 10.1146/annurev-psych-010418-102936

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Theres going to be an explosion in just the sheer number of compounds and also the methods to make them. A hybrid approach Gellman has taken a different approach to novel GLP-1 drugs based on his synthetic beta peptides

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