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These Phase 3 trials enrolled thousands of participants across multiple studies, providing robust evidence for efficacy and safety
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Although the impact of GLP-1RAs on pancreatic cancer risk remains controversial, emerging evidence suggests that chronic low-grade inflammation and proliferative changes may constitute key pathophysiological mechanisms underlying pancreatic cancer development in patients receiving GLP-1RA therapy [8]
Phase 2 SYNERGY-NASH data showed significant reductions in liver fat fraction and NASH resolution rates
