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Fear of long-term effects: Given the ongoing discussions about risks in the medical community, some patients may have concerns about the long-term impact of GLP-1 medications, including dangerous adverse reactions as described on the FDA warning label, like acute kidney injury and hypoglycemia

And at the maximum 15 mg dose, participants achieved a mean weight loss of 22.5%

48 Evidence also showed repopulation of microglia from CNS-endogenous cells following global microglia depletion, which contributes to the dynamic regulation of the microglia population in the adult mouse brain
