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The core active ingredients each carry a defined role: B420 is the formula's primary weight-management strain, with 30+ clinical trial publications examining body fat and waist circumference outcomes in overweight adults Eriomin (lemon extract) is included for its ingredient-level clinical research showing support for natural GLP-1 secretion Dihydroberberine, a modified version of berberine that achieves higher plasma berberine exposure at lower doses, is included for its role in supporting healthy blood sugar levels already within the normal range B420's 6-month RCT in 225 overweight adults (BMI 28-34.9, aged 18-65) showed meaningful changes vs

PPAR-: pioglitazone

Oncology and obesity will drive significant growth through 2028, IQVIA expects

receiving research funding from Sanofi, Roche and IQVIA