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Endocrinol 128:31753182 Rocca AS, Brubaker PL (1999) Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion

What Current Guidance and Studies Say About GLP-1 for PCOS GLP-1 medicines are not FDA-approved specifically for PCOS, but the 2023 international PCOS guideline says medicines like liraglutide and semaglutide could be considered for adults with PCOS who are managing higher weight, using the same general approach used outside PCOS

2 to 12 hours post-injection Blood levels of semaglutide are rising but still relatively low

For most people, peak levels occur around 24 to 48 hours post-injection