microdose glp-1 Injections Microdosing GLP-1 Drugs: What To
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doi: 10.1016/j.jsbmb.2017.06.004 32 YangWJYuTMHuangXSBilottaAJXuLQLuYet al
This prolonged retention might increase intragastric pressure and potentially promote retrograde movement of gastric contents into the esophagus, particularly in patients with pre-existing lower esophageal sphincter dysfunction or hiatal hernia

Fusaroli M, Raschi E, Giunchi V, Menchetti M, Rimondini Giorgini R, De Ponti F, et al

Expert Rev Clin Pharmacol 12(5):471479
