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Weight loss of 515% is recommended to improve many of the complications of overweight/obesity, with greater improvements observed with further weight reductions [5, 9]

Contrave is generally indicated for adults with obesity or those who are overweight and have at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol

doi: 10.1016/0014-5793(81)80288-8 19 LundPKGoodmanRHDeePCHabenerJF
