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Third, while GLP-1RAs are well studied in type 2 diabetes, data for primary prevention in non-diabetic but high-risk individuals remain sparse, including patients with prior ischaemic stroke or transient ischaemic attack and those with high vascular risk driven by obesity, metabolic syndrome, or chronic kidney disease

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However, if new leg pain, swelling, or skin changes accompany the change in appearance, see a vein doctor for an ultrasound evaluation to confirm what is actually happening

If youre thinking about switching, your provider can help you safely transition by starting at the right dose and monitoring your progress