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Description
3.5 Butyrate-activated MPC2 axis rescues mitochondrial energetics to potentiate GLP-1 secretion in diabetic enteroendocrine cells To establish whether butyrate stimulates GLP-1 secretion through MPC2, we performed loss-of-function studies using siRNA-mediated MPC2 knockdown in GLUTag cells

Our previous work has shown that GLP-1 RAs make up 5% of prescriptions within the US (although this trend has increased, as seen in the latest GLP-1 prescribing and dispense report)
10.1002/jcp.29204 114

Willson et al
