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Its premise is an upstream intervention targeting substantial weight reduction to improve key risk factors with the aim to avoid potential downstream complications from multiple co-morbidities, e.g., hypertension, dyslipidaemia, heart failure, kidney disease, NAFLD/NASH or diabetes
UC can vary in severity and is classified into ulcerative proctitis, left-sided colitis, and extensive colitis based on how much of the colon is affected
