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what exactly is glp 1 GLP-1 the Same as Ozempic? Understanding Key Differences GLP-1 Genetics: How Genes Affect
Description
It is highly expressed in the hypothalamus, where it plays a crucial role in the regulation of protein trafficking and recycling, which affect secretory granule biogenesis ( MAGEL2 cause Schaaf-Yang syndrome (MIM: 615547), which is characterized by delayed psychomotor development, frequent intellectual disability, hypotonia, feeding difficulties, and various dysmorphic facial features

In addition to GLP-1 medications, a class of medications used in type 2 diabetes called SGLT-2 inhibitors is also being studied for use with type 1 diabetes

Various GLP-1RAs, including liraglutide, semaglutide, and dulaglutide, demonstrated a reduction in CV outcomes in large CVOTs

Functional studies in rat models have demonstrated that injection of GLP-1 has a dose-dependent effect on reducing feeding behaviors [54, 55], providing evidence of its function as a satiety mediator
