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A: Many researchers investigate Retatrutide in combination with insulin sensitizers, SGLT2 inhibitors, and other metabolic agents to study additive or synergistic effects on glucose and weight regulation

Neither medication is known to significantly alter the metabolism or efficacy of the other

Women taking oral contraceptive pills should be aware that severe vomiting or diarrhoea (which can occur with Wegovy) may affect pill absorption, and additional contraceptive precautions may be needed during and for 7 days after such episodes, as advised by the Faculty of Sexual and Reproductive Healthcare (FSRH)

Some sources of heterogeneity in this study remained unable to be detected