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Mid-range doses (10-20mg) showed optimal efficacy-to-safety ratio Phase III: ~500 subjects, 24 weeks, failed to reach primary endpoint (statistically significant weight loss vs placebo at 24 weeks)
Janssen ERC, van Montfoort AZ, Hollman F, Lambers Heerspink FO
I think we have to reach our own compromises
(2003) Early response to oral cobalamin therapy in older patients with vitamin B12 deficiency
