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Recent studies have demonstrated that histone lactylation plays a critical role in fibrosis progression by promoting histone lactylation at the promoters of profibrotic genes

He is the lead author of the study, published Monday in Nature Medicine

Exenatide and liraglutide additionally lowered the expression of other apoptosis-related proteins, including poly (ADP-ribose) polymerase (PARP), caspase-8, caspase-9, and Bcl-2-associated death promoter (Bad) [87, 92]

These medicines work by mimicking the action of a naturally occurring hormone called GLP-1, which is released from the intestine in response to food intake