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BMC Sports Science, Medicine and and Rehabilitation

They work by stimulating insulin production and decreasing glucagon production, a hormone that raises blood sugar levels

The efficacy and safety of weekly semaglutide (2.4 mg) for the treatment of overweight and obesity was investigated in the Semaglutide Treatment Effect in People with Obesity (STEP) programme, which included individuals with overweight (BMI 27 kg/m 2 ) and complications, including dyslipidaemia, hypertension, sleep apnoea, cardiovascular disease and type 2 diabetes, or individuals with obesity (BMI 30 kg/m 2 ) with or without complications [26, 34,35,36,37,38,39]