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DPP4 inhibitors primarily target the postprandial plasma glucose (PPG), whereas, GLP1 receptor agonists target fasting plasma glucose (FPG) as well as PPG

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This effect was mediated by cAMP and PKA and was absent in mice with genetic deletion of the GLP-1R (54)

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Limitations: What BMI Does Not Tell Us As a nurse, I always explain this carefully: BMI is helpful, but it does NOT show: Your muscle vs

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May have higher risk of GI or metabolic side effects

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