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Description
In people without diabetes, tirzepatide achieved an average weight reduction of 21% and received FDA approval for weight loss in 2023 [24]
doi:10.1056/NEJMoa0802743 2
In addition, specific bile acids can act as signaling molecules by activating the transcription factor FXR or binding to G protein-coupled bile acid receptor-1 (TGR5), both of which are expressed in EECs 270
Many patients have safely reduced steroid or extra DMARD and biologic use
