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First, the SUSTAIN-6 trial showed that semaglutide has a potential benefit on prevention of cardiovascular events [37]

In Phase 3 TRIUMPH-1 (May 21, 2026), the 12 mg arm averaged 28.3% weight loss at 80 weeks, and a higher-BMI subgroup reached 30.3% at 104 weeks

The stratification of incident and prevalent users in this study along with the long follow-up period for prevalent users provided recent insight into the treatment patterns over time in patients who were newly prescribed dulaglutide, s.c
