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Beverly Tchang, an obesity medicine specialist at Cornell University

Appetite, Obesity, Metabolism, and Malignancy: Do Incretin-Mimetic Drugs Reduce Cancer Risk?, Cancer Prevention Research, 19 , 4, (187-196), (2026)

Additionally, P9 induces interleukin-6 (IL-6) secretion from the intestine, which subsequently stimulates GLP-1 secretion by intestinal L-cells and pancreatic -cells, and also affects Icam2 mRNA expression, which suggests the normal expression of Icam-2 and the effects of P9 in glucose homeostasis may require IL-6 [160] (Fig

When nutrients reach the lower part of the small intestine, specialized cells release GLP-1 as part of the bodys normal digestive and metabolic response