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This comprehensive analysis offers forward-looking guidance for future research and clinical interventions addressing diabetes-associated male infertility.

For optimal outcomes, incorporate 30 minutes of movement daily, like walking or yoga, which naturally boosts GLP-1 release

The mouse models included lean mice (C57BL/6J and NSY.B6- a / a ), obese diabetic mice (NSY.B6- Ay / a ), proglucagon-deficient mice ( Gcg -/-), glucose-dependent insulinotropic polypeptide (GIP) receptor-deficient mice ( Gipr -/-), and ATP-sensitive potassium channel (KATP channel)-deficient mice ( Kcnj11 -/-)