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Once daily teduglutide administration in human subjects with PN-dependent SBS resulted in increased fluid and energy absorption, while reducing the requirements for PN, in two separate placebo-controlled Phase 3 studies (67, 68)

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NICE recommends early laparoscopic cholecystectomy (gallbladder removal) for acute cholecystitis where appropriate

In the central nervous system, agents like exedin-4 and liraglutide reduce neuroinflammation by inhibiting microglial activation and cytokine production (IL-1, IL-6, TNF- ), while preserving neuronal integrity and preventing cognitive dysfunction associated with sepsis