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The drug causes thyroid cancer in rodents, but the risk to humans is unknown

In endometrial cancer cells, liraglutide induces an upregulation in progesterone receptor (PGR) mRNA levels, promotes its protein expression, markedly enhances phosphorylated AMPK levels, and downregulates its downstream effector molecule p-P71S6K, ultimately inhibiting cell viability [58]

GLP-1 agonists, Cleveland Clinic (2023) Nutritional modulation of endogenous glucagon-like peptide-1 secretion: A review , Nutrition & Metabolism (2016) Closing Americas fiber intake gap, American Journal of Lifestyle Medicine (2016) Easy ways to boost fiber in your daily diet, Academy of Nutrition and Dietetics (2021) The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon, The American Journal of Physiology-Gastrointestinal and Liver Physiology (2018) Mediterranean diet effects on Type 2 diabetes prevention, disease progression, and related mechanisms