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Between 30 million and 50 million US adults could be taking a GLP-1 by 2034. In December 2024, 1.9 million prescriptions of GLP-1s to treat obesity (as opposed to diabetes, for example) were filled, nearly quadruple the number YoY, per IQVIA

Semaglutide and other GLP-1 medications may influence cortisol regulation during weight loss, though direct cortisol suppression is not their primary mechanism