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Improving the dysfunctional flora structure is beneficial to the functional recovery after spinal cord injury Short-chain fatty acid regulate the inflammatory process and inhibit the neurotoxicity and secondary injury of microglia Microglia can rapidly transform into activated macrophages and produce toxic molecules that mediate lipid peroxidation, eventually leading to subsequent tissue damage and axonal contraction after SCI (Kigerl et al., 2009)

PMCID: PMC8900094

Patients with pre-existing chronic kidney disease, advanced age, or concurrent use of medications affecting kidney function require enhanced monitoring during treatment