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In terms of ventricular load, SGLT2i reduce cardiac load via osmotic diuresis and enhance urinary sodium excretion while also decreasing arterial stiffness and improving endothelial function [109]

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Acknowledgements Editorial support was provided by Richard Ogilvy-Stewart of Apollo, OPEN Health Communications, and funded by Novo Nordisk A/S, in accordance with Good Publication Practice guidelines (www.ismpp.org/gpp-2022)

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