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The GIP pathway in particular appears to play a role in how tirzepatide affects fat distribution, which is one area where it differs meaningfully from GLP-1-only medications

Full safety information should be reviewed with your prescribing clinician

We discuss a case of a 38-year-old woman with advanced endometrial cancer who presents with acute abdominal pain, found to have splenic and renal infarcts, severe aortic regurgitation, and persistently negative blood cultures, ultimately diagnosed with nonbacterial thrombotic endocarditis (NBTE)