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GLP-1 receptor agonists reduce both IL-6 and TNF-alpha secretion

However, other cells, primarily including muscle cells and adipose tissue, rely heavily on the insulin hormone to take up glucose

The fatigue you feel is often your bodys response to an energy shortage not a side effect of the drug itself

Common side effects include : Diarrhea Vomiting Stomach pain Upset stomach or indigestion Dizziness Burping Flatulence Stomach flu-like symptoms Heartburn or acid reflux Common cold-like symptoms Hypoglycemia (low blood sugar) in people with type 2 diabetes More serious side effects are also possible but are less likely