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Benefits of Semaglutide The primary use of semaglutide is to help manage type 2 diabetes and support weight loss

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Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

DA-1241 and semaglutide monotherapy each improved NAS (2-point) in 21% of mice, whereas combination treatment led to marked improvements (2-point in 80% of mice and 1-point in all mice), driven by reduction in steatosis and lobular inflammation scores