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Description
It stimulates the GLP-1 receptor in pancreatic ?-cells to enhance glucose-dependent insulin secretion, suppresses pancreatic ?-cell glucagon secretion, and directly acts on appetite-regulating centers in the brain
Some patients might need treatment adjustments based on how their body responds

Mean change in fasting glucose at 40 weeks was 30.1 mg/dL with retatrutide 4 mg, 31.9 mg/dL with retatrutide 9 mg and 30.8 mg/dL with retatrutide 12 mg compared with 1 mg/dL with placebo
If you are traveling across multiple time zones, you may need to decide whether to stick to your home time or adjust to the local time
