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Tirzepatide Is Sufficient (Stay Put) If: You're close to your target weight: If tirzepatide has gotten you 8090% of the way to your goal, switching drugs mid-course introduces titration disruption and new side effects for a marginal numerical gain
Bariatric surgery remains the most effective long-term option for severe obesity, with strong data on weight loss maintenance and obesity-related disease improvement (ASMBS)
