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McDiarmid Supplementary information Supplementary Information accompanies this paper at (10.1038/s41398-020-0756-3)

Biomed Pharmacother 2021;140:111778.ArticlePubMed 58

How common is GLP-1 hair loss

Pharmacologically, signaling studies demonstrate that tirzepatide mimics the actions of native GIP at the GIP receptor but shows bias at the GLP-1 receptor to favor cAMP generation over -arrestin recruitment, coincident with a weaker ability to drive GLP-1 receptor internalization compared with GLP-1
