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Positive correlations with SA were identified for all risk factors: BMI (OR 1.51 [95%CI 1.471.56], P = 4.08 10 162 ), current tobacco smoking (OR 1.21 [95%CI 1.061.38], P = 5.45 10 3 ), and alcohol consumption (OR 1.12 [95% CI 1.001.24], P = 4.42 10 2 )

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For a long time, the manifestation of depressive symptoms has been also associated with the deficits in neurotrophic factor action in the brain [51], especially highlighting the role of diminished brain-derived neurotrophic factor (BDNF) signaling as important for the pathogenesis of this mental disorder [52]