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GI Symptom Screen : Document any active nausea, vomiting, or diarrhea that may indicate clinical dehydration
Preliminary observations from a Phase III clinical trial (NCT02896192) suggested that among 10 patients with POMC -deficient obesity (aged 6 years, BMI 30 kg/m 2 ), approximately 80% achieved a weight reduction of 10% after 1 year of treatment with setmelanotide following individualized dose titration
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