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Autoimmune Thyroid Disorders Current evidence for GLP-1 RAs in autoimmune thyroid disorders remains primarily mechanistic with limited clinical data, though the theoretical rationale is compelling

Sequence comparison among endogenous hormones, approved drugs and triple agonists revealed that the peptide sequence is conserved in the N-terminal region (residues 49), with variations primarily occurring in the middle region (residues 1021) (Fig