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In the technical scheme of the invention, in the step (4), the method for removing Alloc is to use Pd 0 (Ph 3 P) 4 And Me 2 NHBH 3 Combination of (2) or Pd 0 (Ph 3 P) 4 And PhSiH 3 In which Pd is removed 0 (Ph 3 P) 4 The dosage of the compound is 0.05 to 1.0 time of the molar weight of the Alloc protecting group, preferably 0.1 to 0.5 time

This increase in melanin produces a patch of skin thats darker than the skin surrounding it
